BC Cardiovascular Community at the Canadian Cardiovascular Congress

Rising Stars: Dr. Marc Deyell


Dr. Marc Deyell is Cardiac Electrophysiologist with the Division of Cardiology at UBC.  He received his MD from the University of Alberta and completed his electrophysiology training at UBC and the University of Pennsylvania in Philadelphia.  His clinical interests focus on the management of ventricular arrhythmias including premature ventricular complexes (PVCs) and scar-related ventricular tachycardia.  His research interests focus on the epidemiology and impact of PVCs in heart failure, evaluating outcomes after ablation and evaluating therapy for ventricular tachycardia.

Lay summary of program/project:

Premature ventricular contractions (PVCs) are extra heart beats arising from the ventricular, or pumping, chambers of the heart.  Frequent PVCs are rare in the general population but more common in patients with congestive heart failure (CHF) who have poor heart function.  Frequent PVCs may be further worsening heart function in these patients or interfering with other therapies for CHF.  My research program aims to establish how common frequent PVCs are in the CHF population and to assess whether frequent PVCs affect health outcomes in these patients.   Despite the advances over the last 30 years, CHF remains a disease with a poor prognosis and the treatment of CHF patients consumes a significant amount of health care resources.  Effective therapies already exist for treating PVCs in patients with heart failure.  This research will provide the basis for evaluating whether PVCs are a new treatment target to improve the health and well-being of patients with CHF.

Medical summary of program/project:

The primary focus of my research program is the epidemiology, etiology and treatment of frequent PVCs. The majority of contemporary PVC research has focused on enhancing outcomes with catheter ablation. However, much of the etiology, pathophysiology and epidemiology of frequent PVCs remains unknown.  The centralized cardiology care and strength of administrative data in British Columbia present a unique opportunity to answer many fundamental questions regarding frequent PVCs on a broader level. The BC PVC research program focuses on two areas/populations: 1) epidemiology and treatment of frequent PVCs in patients with heart failure; 2) epidemiology and treatment of idiopathic frequent PVCs among patients with normal cardiac function.  In collaboration with heart failure and electrophysiology colleagues, I am in the planning process for studies examining the prevalence of frequent PVCs among patients referred to heart function clinics and in patients referred for primary prevention ICD or CRT-D therapy. Rigorous baseline and long-term outcome data is sorely lacking for patients with frequent PVCs and normal LV function.  My goal is to develop a BC-wide registry with collaboration from electrophysiologists across the Province.