Director, Providence Heart + Lung Institute at St Paul’s Hospital.
Bruce McManus is Professor, Department of Pathology and Laboratory Medicine, at the University of British Columbia. Since 2006, he has served as Director of the James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research located at St. Paul’s Hospital and as the Scientific Director of the Heart Centre at St. Paul’s Hospital – Providence Health Care. In September 2007, Dr. McManus was appointed as the inaugural Director of the recently launched Providence Heart + Lung Institute at St. Paul’s Hospital. In February of 2008, Dr. McManus successfully led the Prevention of Organ Failure (PROOF) team to a $15 million funding award to establish a Centre for Excellence and Commercialization in Research (CECR), in the Networks of Centres of Excellence (NCE) program, for which he also now serves as Director.
Dr. McManus served as the inaugural Scientific Director of the Institute of Circulatory and Respiratory Health, Canadian Institutes of Health Research, from December 2000 until April 2006. In this capacity, he led the development and implementation of a strategic research plan for Canada to address scientific questions related to cardiac, respiratory, vascular, brain (stroke), blood, sleep, and intensive care-related disorders and diseases.
Dr. McManus received BA and MD degrees at The University of Saskatchewan, an MSc in Applied Physiology from Pennsylvania State University, and PhD in Exercise Physiology and Biochemistry from the University of Toledo. He pursued post-doctoral fellowships in Environmental Physiology at the University of California - Santa Barbara and in Cardiovascular and Pulmonary Pathology at the National Heart, Lung, and Blood Institute in Bethesda, MD. Residency training at the Peter Bent Brigham Hospital - Harvard University in Internal Medicine and Pathology, was followed by specialization in Cardiovascular Pathology. Following 11 years as a faculty member at the University of Nebraska Medical Centre, including a sabbatical as John F. Fogarty Senior International Fellow at the Max Planck Institute for Biochemistry, Martinsried, Germany, Dr. McManus joined the Faculty of Medicine of the University of British Columbia as Department Head of Pathology and Laboratory Medicine in July 1993, a post he held until December, 2000. Dr. McManus is a Fellow of the Royal College of Physicians and Surgeons of Canada, the College of American Pathologists, the American College of Cardiology and the American College of Chest Physicians.
Dr. McManus’ investigative program is focused on mechanisms, consequences, detection and prevention of injury and repair involved in inflammatory diseases of the heart and blood vessels, with particular emphasis on enteroviral infections of the heart and transplant vascular disease. He works in an interdisciplinary setting on questions for which answers are critically enabled by computational sciences including biomarker discovery and validation, information acquisition, annotation, and use, and registry development to support heart and lung research. Dr. McManus has co-authored over 300 peer-reviewed publications, as well as many chapters. He has edited four books. He has served as Councilor for the International Society for Heart Research and for the American Society for Investigative Pathology. He is past-president of the Society for Cardiovascular Pathology. He currently serves on the editorial board of several professional and scientific journals, and on many advisory committees and boards. He has long been committed to training and mentoring scientist trainees across a range of disciplines. He has convened many public and private sector partnerships in research.
Dr. McManus has been recognized for his scientific contributions by numerous institutions through visiting professorships and lectureships. He was co-recipient of the prestigious Max Planck Research Award with Dr. Reinhard Kandolf in 1991. He was elected to the Royal Society of Canada as a Fellow of the Academy of Sciences in 2002. He received a UBC Killam Research Prize- Senior Scientist Category, and was elected as Fellow of the International Academy of Cardiovascular Sciences in 2003. In 2005, he was elected as an inaugural Fellow of the Canadian Academy of Health Sciences. In 2006 Dr. McManus received the BC Innovation Council’s Lieutenant Governor’s Technology Innovation Award. He has also been recently honoured with the David Hardwick Lifetime Achievement Award and the UBC Distinguished Medical Lecturer Award.